GLP-1

Building a Successful GLP-1 Program: Lessons from the Field

Discover proven strategies for launching and scaling a GLP-1 weight management program based on real-world experience.

The GLP-1 Opportunity

GLP-1 programs can be a strong growth engine for telehealth clinics—when they’re run like a complete program, not just a prescription workflow. Success comes from the full system: screening, follow-ups, retention, and operations.

Note: This article is for informational purposes only and does not provide medical advice. Clinical decisions should be made by licensed providers.

Patient Screening and Eligibility

Initial Assessment

A thorough initial assessment helps protect patients and reduces downstream churn. Common steps include:

  1. Medical history review: Identify risk factors and contraindications
  2. BMI and clinical context: Confirm the program is a fit
  3. Lifestyle and readiness: Set expectations and support needs
  4. Coverage and cost clarity: Align early on insurance vs. self-pay

Contraindications to Consider

Examples of contraindications commonly referenced in GLP-1 labeling and clinical guidance include:

  • History of medullary thyroid carcinoma
  • Multiple Endocrine Neoplasia syndrome type 2
  • Severe gastrointestinal disease
  • Pregnancy or planning pregnancy

Your program should reflect your clinical policies and local requirements.

Medication Management

Starting Doses

Most programs start conservatively and titrate based on tolerability and response. A typical approach is:

  • Weeks 1–4: Starting dose
  • Weeks 5–8: First increase (if appropriate)
  • Week 9+: Maintenance or further titration as clinically indicated

Monitoring and Follow-up

Consistent follow-ups are one of the biggest levers for retention and safety.

A simple baseline schedule many programs use:

  • Week 2: Side-effect check-in
  • Month 1: Weight progress + tolerability review
  • Months 2–3: Efficacy evaluation and plan adjustment
  • Ongoing: Monthly follow-ups or as needed

Patient Retention Strategies

Retention isn’t just reminders—it’s making the program feel guided and predictable.

Communication

  • Automated reminders for check-ins and refills
  • Educational content that answers common questions early
  • Fast support loops for patient questions (without forcing calls)
  • Clear expectations around timelines, titration, and outcomes

Engagement

  • Progress tracking to reinforce momentum
  • Goal setting with realistic milestones
  • Positive reinforcement at key moments (week 2, month 1, etc.)
  • Personalized follow-ups based on risk and adherence signals

Scaling Your Program

Automation

Once you scale beyond a small patient base, automation becomes essential:

  • Intake forms that reduce manual work and triage faster
  • Self-serve scheduling where it makes sense
  • Billing workflows that reduce back-and-forth and failed payments
  • Follow-ups triggered by patient behavior (missed check-in, refill due)

Team Structure

A scalable program usually splits work across roles:

  • Clinical team: providers + nurses
  • Support team: patient coordinators
  • Operations: billing and program admin
  • Platform ops: tooling, integrations, reporting

Common Challenges and Solutions

Challenge: High patient dropout

Solution: Improve early-week experience:

  • Week 1–2 check-ins with clear guidance
  • Simple progress tracking
  • Low-friction messaging support
  • Better expectation setting (timeline and common side effects)

Challenge: Insurance denials

Solution: Reduce friction upfront:

  • Pre-verify coverage where possible
  • Submit complete documentation
  • Track prior authorization status clearly
  • Offer a self-pay path for patients who want speed and predictability

Challenge: Provider burnout

Solution: Design for throughput:

  • Templates for common scenarios
  • Delegate non-clinical tasks to ops/support
  • Batch similar follow-ups
  • Use async workflows where possible

Technology Solutions

A platform won’t “fix” the program, but it can remove the operational drag that kills scale.

Look for systems that support:

  • Intake automation to reduce manual data entry
  • Standardized workflows for follow-ups and documentation
  • Billing + subscriptions to simplify renewals
  • Patient portal to reduce repetitive support questions
  • Analytics to monitor funnel + retention

Measuring Success

Track the metrics that drive long-term performance:

  • Retention rate: % of patients continuing month-to-month
  • Time to first touch: how quickly patients get started
  • Completion rate: intake + follow-ups completed on time
  • Support load: tickets/messages per active patient
  • Revenue per patient: by cohort and program entry point

Be careful with “average weight loss” as a business KPI—outcomes vary, and reporting should be clinically responsible and compliant with your policies.

Conclusion

A successful GLP-1 program is built on consistency: screening, structured follow-ups, and retention workflows that patients actually complete. When you remove operational friction, your team can focus on care quality instead of chasing logistics.

Interested in learning more? Explore our GLP-1 solutions or contact our team to discuss your workflows.

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